Annual report pursuant to Section 13 and 15(d)

Equity Incentive Plans - Stock-based Compensation Expense (Details)

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Equity Incentive Plans - Stock-based Compensation Expense (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Stock based compensation expense $ 156 $ 220 $ 17
Research and development      
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Stock based compensation expense 137 207 14
Selling, general, and administrative      
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Stock based compensation expense $ 19 $ 13 $ 3